COVID-19 Genetic Risk Variant Protects Against HIV

 

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A variant inherited from Neanderthals that poses a threat to COVID-19 reduces a person's risk of contracting HIV by 27 percent.

Congenital genetic variants can increase or decrease the risk of severe COVID-19. An important variant that we inherited from Neanderthals, which poses a severe COVID-19 challenge, is surprisingly common. This raises the question of whether it is actually beneficial to carry the variant in question. The new study by Hugo Zeberg, a researcher at the Max Planck Institute Department of Evolutionary Anthropology and Sweden's Karolinska Institutet, shows that the same genetic variant that increases the risk of contracting severe COVID-19 also protects against another serious disease: The variant increases a person's risk of contracting HIV by 27 percent. rate decreases. The study was published last week in the journal Proceedings of the National Academy of Sciences.


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